Project status: July 2021
Our research is going on! Collaborators just started biological evaluation of 30 chemical compounds selected in SiDock@home for targets 3CLpro and PLpro. Biological evaluation in vitro works with the most prospective results that your computers have selected in silico. The process is iterative and will involve hundreds of experiments.
With your help, we have already processed 4 targets and 43% of the fifth one. Further workunits will be created basing on the biological evaluation and the latest scientific knowledge about the targets.
Many thanks and best wishes,
Team of SiDock@home
9 Jul 2021, 18:21:50 UTC · Discuss
Donations to SiDock@home
Drug development is a time-consuming and costly process. With help of your computers, our team is able to speed up discovery of prospective candidates for in vitro tests. At the same time, the volume of biological evaluation is limited by funding. We are in constant search for additional sources, and, since SiDock@home allows the participants to earn Gridcoins, we find it a good idea to accept voluntary donations. If you feel like donating to the project, please use one of the listed options.
9 Jul 2021, 18:18:53 UTC · Discuss
SiDock@home is whitelisted in Gridcoin
since today, SiDock@home is whitelisted in Gridcoin. It means that you can receive the Gridcoin cryptocurrency for contributing to SiDock@home. For instructions, please refer to the official website of Gridcoin. For a description how Gridcoin works, refer to their whitepaper. This technology is yet new to our team, but we will do our best to understand it and help you to use it.
28 Jun 2021, 12:23:44 UTC · Discuss
SiDock@home is going to join Gridcoin
we want to be whitelisted in Gridcoin (anytime), so you will be able to receive this cryptocurrency for scientific computing. We believe that Gridсoin is ethical. This is also a chance to increase awareness of the project.
6 Jun 2021, 19:00:14 UTC · Discuss
Release CmDock v 0.1.3
The following changes will be transparent, but if you are interested in technical details, then here they are. A new application cmdock-boinc-zcp has been released, including the new CmDock v0.1.3 release with (z)ipped input, (c)heckpoints and enhanced (p)rogress bar. In addition, a new docking experiment will begin under a new protocol.
Thanks to the CmDock team and pschoefer & walli for the release!
28 May 2021, 11:07:44 UTC · Discuss
Sidock@home is an international volunteer computing project aimed at drug discovery. The first mission of the project is discovery of possible drugs against the SARS-CoV-2 virus. It started as an extension of the project COVID.SI to engage the BOINC community into the drug discovery.
You can help with your computer. With the help of BOINC, you will download a subset of compounds on your computer, examine the compounds in the context of the studied target and send the results to a server where they are collected for later analysis.
For account creation please use a Crunch_4Science invitation code. It is not needed when registering by BOINC Manager.
Already joined? Log in.
We are going to use donation money for biological evaluation of results.
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