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BOINC Census 2022, be counted!
The BOINC Census is a yearly effort aimed at finding out who uses BOINC, what they like about it, and what changes they want to see in the future. Filling out the census is a great way to support this project, the wider BOINC community, and have your input heard for future bug bounties. The census is sponsored by the Science Commons Initiative, and the results will be published in an aggregate, anonymized fashion at the completion of the census. Please take 5 minutes to fill out the census at https://app.fillout.com/flow/esDGuRswWfus
17 Nov 2022, 13:24:51 UTC · Discuss


Target 21: corona_TMPRSS2_v1
Dear Participants,

TMPRSS2 is a type II transmembrane protease with broad expression in epithelial cells of the respiratory and gastrointestinal human tracts. It is a cofactor in SARS-CoV-2 entry, and primes viral proteins. Namely, TMPRSS2 cleaves the viral Spro to expose the fusion peptide for cell entry. We are therefore examining TMPRSS2 as a promising strategy to block viral infection in a host-directed therapeutic and/or prophylactic manner. This work is also a a part of larger viral-host protease inhibition study campaign.

With best wishes,
Team SiDock@home
17 Nov 2022, 13:21:56 UTC · Discuss


Temporarily work unavailabilities
Dear participants, after sending last tasks for target 20 (corona_DHODH_v1) we will start the experiment with one of already processed targets but with new parameters. Results for this tasks will be large and we will slow down the creation of new tasks for reducing load on network infrastructure. Often there will be no tasks.

Thank you for project support!
24 Oct 2022, 23:25:21 UTC · Discuss


CmDock new release pending
Dear SiDock@home community,

Just a little update on the development of our CmD software. We were planning to release CmD 0.1.5.; however, we decided to wait a bit. Namely, we want to implement a robust testing (regression, unit) pipeline and lay the work for future software optimization. Therefore we would like to implement a cross-platform consistent pseudo-random number generation that would mean - write once, compile and test everywhere... We think this can be achieved relatively quickly.

On the other front, Mac builds are being tested and we will provide the community with Mac builds through homebrew platform. We will publish the news on future release here.

All the best,
Marko
22 Jul 2022, 15:33:02 UTC · Discuss


Project status: May 2022
Dear all,

with your help, we have processed 15 targets already! It is a huge computational work, the results of which are being processed by our team and colleagues. We are working on two papers which will be available to the public as early as possible. We also continue computations for next targets. During March, April and May, project's performance was fluctuating around 250 Teraflops. We took this advantage to prioritize SARS-CoV-2 targets on top of the other research. At the end of spring 2022, we are 6426 active participants with 4493 computers.

With best wishes,
Natalia and the team of SiDock@home
31 May 2022, 19:44:33 UTC · Discuss


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What is SiDock@home?

Sidock@home is an international volunteer computing project aimed at drug discovery. The first mission of the project is discovery of possible drugs against the SARS-CoV-2 virus. It started as an extension of the project  COVID.SI to engage the BOINC community into the drug discovery.

You can help with your computer. With the help of BOINC, you will download a subset of compounds on your computer, examine the compounds in the context of the studied target and send the results to a server where they are collected for later analysis.

For account creation please use a Crunch_4Science invitation code. It is not needed when registering by BOINC Manager.

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User profile Profile ltgobis
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